SCHEMBL19618145

SCHEMBL19618145

CC(C)(N)c1ncnc2[nH]cnc12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.31
PDPK1 O15530 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130108 0.86 HPGD (0.39) HPGD
SCHEMBL6745188 0.83 HPGD (0.30) HPGD
SCHEMBL18879374 0.80 HTT (0.31)
SCHEMBL19261349 0.80 HTT (0.31)
SCHEMBL5720577 0.80 MEN1 (0.33)
SCHEMBL5720237 0.78 LRRK2 (0.31)
SCHEMBL2934090 0.78 PARP1 (0.34)
SCHEMBL19618124 0.78 HTT (0.33)
SCHEMBL19779078 0.75 HTT (0.33) HPGD
SCHEMBL19618176 0.75 HTT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822131-B2 Certain chemical entities, compositions and methods INTELLIKINE LLC (US) 2017-11-21 US disclosed