SCHEMBL19618296

SCHEMBL19618296

c1ccc(-c2ccc(-c3cc(-c4ccc5ccccc5c4)nc4ccc(-c5ccc6ccccc6c5)cc34)cc2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.50
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
TSHR P16473 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPK1 P28482 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TP53 P04637 1/20 0.46
PKM P14618 1/20 0.46
KLF5 Q13887 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RECQL P46063 1/20 0.46
CYP1A1 P04798 1/20 0.46
CYP1B1 Q16678 1/20 0.46
AURKA O14965 1/20 0.45
AURKB Q96GD4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19618290 0.92 SIRT2 (0.45) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19618582 0.91 DHODH (0.48) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19009636 0.89 KDM4E (0.48) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19618360 0.89 DHODH (0.55) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19618351 0.89 DHODH (0.55) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19618310 0.88 MEN1 (0.47) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19618368 0.88 DHODH (0.51) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19618584 0.85 DHODH (0.44) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19618352 0.85 DHODH (0.51) DHODHKDM4EALDH1A1MAPTLMNA
SCHEMBL19618349 0.85 DHODH (0.51) DHODHKDM4EALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9825242-B2 Compound for organic optoelectric device, organic light-emitting diode including same, display device including organic light-emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-11-21 US disclosed
US-9825242-B2 Compound for organic optoelectric device, organic light-emitting diode including same, display device including organic light-emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-11-21 US disclosed