Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.66 |
| ▸ | TNK2 | Q07912 | 17/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748786 | 0.89 | BTK (0.71) | BTKTNK2 | |
| SCHEMBL19619153 | 0.82 | BTK (0.49) | BTKTNK2 | |
| SCHEMBL16748775 | 0.81 | BTK (0.61) | BTKTNK2 | |
| SCHEMBL16748812 | 0.81 | BTK (0.87) | BTKTNK2 | |
| SCHEMBL16748808 | 0.81 | BTK (0.83) | BTKTNK2 | |
| SCHEMBL16748852 | 0.81 | BTK (0.57) | BTKTNK2 | |
| SCHEMBL16748849 | 0.80 | BTK (0.84) | BTKTNK2 | |
| SCHEMBL16748831 | 0.79 | BTK (0.78) | BTKTNK2 | |
| SCHEMBL16748893 | 0.79 | BTK (1.00) | BTKTNK2 | |
| SCHEMBL16748788 | 0.79 | BTK (0.71) | BTKTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822120-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-11-21 | — | — | US | disclosed |