SCHEMBL1962151

SCHEMBL1962151

CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCCN)OCCCCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 2/20 0.67
LPAR1 Q92633 4/20 0.60
LPAR3 Q9UBY5 4/20 0.60
LPAR2 Q9HBW0 1/20 0.53
TLR2 O60603 2/20 0.50
RECQL P46063 1/20 0.48
P2RY10 O00398 6/20 0.47
PLA2G2D Q9UNK4 1/20 0.47
GPR34 Q9UPC5 2/20 0.47
FABP3 P05413 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12345678 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL2233966 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL12345664 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL15166560 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL12345694 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL705428 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL2175237 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL703055 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL12345706 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2
SCHEMBL2234099 1.00 PLA2G2C (0.67) PLA2G2CLPAR1LPAR3LPAR2TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010052718-A9 OXIDIZED LIPID COMPOUNDS AND USES THEREOF VASCULAR BIOGENICS LTD. (IL) 2011-06-16 WO disclosed