Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.67 |
| ▸ | PDE4A | P27815 | 12/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | PDE1A | P54750 | 1/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.61 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527621 | 0.88 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2530493 | 0.86 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2528594 | 0.85 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2527455 | 0.85 | PDE4B (0.72) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2533463 | 0.84 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL14748418 | 0.84 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2527878 | 0.84 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL2529581 | 0.84 | PDE4B (0.70) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| SCHEMBL15011437 | 0.84 | PDE4B (0.72) | PDE4BPDE4APDE4CPDE4DCHRM1 | |
| Hydrochloric Acid SCHEMBL2530428 | 0.83 | PDE4B (0.68) | PDE4BPDE4APDE4CPDE4DCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |