Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379113 | 0.91 | PIK3CA (0.60) | PIK3CAPIK3R1 | |
| SCHEMBL2377050 | 0.90 | PIK3CA (0.69) | PIK3CAPIK3R1 | |
| SCHEMBL2375230 | 0.90 | PIK3CA (0.63) | PIK3CAPIK3R1 | |
| SCHEMBL2378443 | 0.89 | PIK3CA (0.55) | PIK3CAPIK3R1 | |
| SCHEMBL2379287 | 0.89 | PIK3CA (0.64) | PIK3CAPIK3R1 | |
| SCHEMBL2378281 | 0.89 | PIK3CA (0.56) | PIK3CAPIK3R1 | |
| SCHEMBL2377678 | 0.88 | PIK3CA (0.56) | PIK3CAPIK3R1 | |
| SCHEMBL2379413 | 0.88 | PIK3CA (0.64) | PIK3CAPIK3R1 | |
| SCHEMBL2378487 | 0.88 | PIK3CA (0.55) | PIK3CAPIK3R1 | |
| SCHEMBL2378717 | 0.88 | PIK3CA (0.54) | PIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | disclosed |