Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2378446 | 0.92 | PIK3CA (0.72) | PIK3CA | |
| SCHEMBL2377465 | 0.88 | PIK3CA (0.71) | PIK3CA | |
| SCHEMBL2377316 | 0.83 | PIK3CA (0.82) | PIK3CA | |
| SCHEMBL2378202 | 0.82 | PIK3CA (0.77) | PIK3CA | |
| SCHEMBL12247649 | 0.81 | PIK3CA (0.78) | PIK3CA | |
| SCHEMBL19623464 | 0.81 | PIK3CA (0.80) | PIK3CA | |
| SCHEMBL2377183 | 0.80 | PIK3CA (0.73) | PIK3CA | |
| SCHEMBL19623392 | 0.80 | PIK3CA (0.64) | PIK3CA | |
| SCHEMBL3831151 | 0.80 | PIK3CA (0.78) | PIK3CA | |
| Trifluoroacetic Acid SCHEMBL2377840 | 0.79 | PIK3CA (0.69) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | disclosed |