Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2378589 | 0.89 | PIK3CA (0.66) | PIK3CAPIK3R1 | |
| SCHEMBL2378850 | 0.81 | PIK3CA (0.56) | PIK3CAPIK3R1 | |
| SCHEMBL2376678 | 0.80 | PIK3CA (1.00) | PIK3CAPIK3R1 | |
| SCHEMBL2377822 | 0.80 | PIK3CA (0.78) | PIK3CAPIK3R1 | |
| SCHEMBL2376229 | 0.79 | PIK3CA (1.00) | PIK3CAPIK3R1 | |
| SCHEMBL2376432 | 0.79 | PIK3CA (0.73) | PIK3CAPIK3R1 | |
| SCHEMBL12246544 | 0.79 | PIK3CA (0.73) | PIK3CAPIK3R1 | |
| SCHEMBL2375595 | 0.79 | PIK3CA (0.63) | PIK3CAPIK3R1 | |
| SCHEMBL19623710 | 0.79 | PIK3CA (0.68) | PIK3CAPIK3R1 | |
| SCHEMBL2376110 | 0.79 | PIK3CA (0.63) | PIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | disclosed |