Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624285 | 0.80 | — | — | |
| SCHEMBL26781418 | 0.75 | — | — | |
| SCHEMBL21770846 | 0.75 | TDP1 (0.36) | TDP1 | |
| SCHEMBL21608962 | 0.75 | TDP1 (0.36) | TDP1 | |
| SCHEMBL21608992 | 0.73 | TDP1 (0.35) | TDP1 | |
| SCHEMBL18721174 | 0.73 | TDP1 (0.35) | TDP1 | |
| SCHEMBL19423950 | 0.71 | — | — | |
| SCHEMBL24576957 | 0.70 | TDP1 (0.36) | TDP1 | |
| SCHEMBL29314475 | 0.69 | — | — | |
| SCHEMBL18927522 | 0.69 | TDP1 (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246330-A1 | IMIDAZOLES AS HISTONE DEMETHYLASE INHIBITORS | Istituto Europeo di Oncologia S.r.l. (IT) | 2017-11-22 | — | — | EP | disclosed |