Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544600 | 1.00 | BTK (0.51) | BTKGPR119CHEK2HPGDKDM4E | |
| SCHEMBL19544682 | 0.95 | BTK (0.48) | BTKGPR119CHEK2HPGDKDM4E | |
| SCHEMBL19544905 | 0.94 | BTK (0.49) | BTKGPR119CHEK2 | |
| SCHEMBL19624659 | 0.94 | BTK (0.47) | BTKGPR119CHEK2HPGDKDM4E | |
| SCHEMBL19544647 | 0.91 | BTK (0.55) | BTK | |
| SCHEMBL19544659 | 0.91 | BTK (0.55) | BTK | |
| SCHEMBL25060355 | 0.90 | BTK (0.48) | BTKGPR119CHEK2ALDH1A1 | |
| SCHEMBL19544304 | 0.90 | BTK (0.48) | BTKGPR119CHEK2ALDH1A1 | |
| SCHEMBL19624846 | 0.90 | CHEK2 (0.45) | BTKGPR119CHEK2HPGDKDM4E | |
| SCHEMBL19544728 | 0.89 | BTK (0.54) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |