Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.53 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544648 | 0.91 | BTK (0.48) | BTKEGFRKITFLT3 | |
| SCHEMBL19624840 | 0.89 | BTK (0.52) | BTKEGFRKITFLT3 | |
| SCHEMBL19545099 | 0.88 | BTK (0.51) | BTKEGFRKITFLT3 | |
| SCHEMBL19544647 | 0.86 | BTK (0.55) | BTKEGFRSRC | |
| SCHEMBL19544659 | 0.86 | BTK (0.55) | BTKEGFRSRC | |
| SCHEMBL19533629 | 0.86 | BTK (0.49) | BTKEGFRKITFLT3 | |
| SCHEMBL19544728 | 0.84 | BTK (0.54) | BTKEGFRSRC | |
| SCHEMBL20411964 | 0.84 | BTK (0.62) | BTKEGFRSRC | |
| SCHEMBL19533600 | 0.83 | BTK (0.51) | BTKEGFRKITFLT3 | |
| SCHEMBL15756475 | 0.82 | BTK (0.73) | BTKEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |