Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544623 | 0.93 | BTK (0.46) | BTKKITFLT3EGFR | |
| SCHEMBL19624840 | 0.91 | BTK (0.52) | BTKKITFLT3EGFR | |
| SCHEMBL19544596 | 0.91 | BTK (0.51) | BTKKITFLT3EGFR | |
| SCHEMBL19624846 | 0.86 | CHEK2 (0.45) | BTK | |
| SCHEMBL19533567 | 0.85 | BTK (0.49) | BTKKITFLT3EGFR | |
| SCHEMBL19545099 | 0.83 | BTK (0.51) | BTKKITFLT3EGFR | |
| SCHEMBL19624953 | 0.83 | CHEK2 (0.42) | BTK | |
| SCHEMBL19624791 | 0.82 | RET (0.42) | BTKEGFR | |
| SCHEMBL19544647 | 0.81 | BTK (0.55) | BTKEGFR | |
| SCHEMBL19544659 | 0.81 | BTK (0.55) | BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |