Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965278 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL17785247 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL4442261 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL1963415 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL1962738 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL4431826 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL1962732 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL1963385 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL2310731 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 | |
| SCHEMBL4444963 | 0.93 | FFAR4 (0.55) | ALDH1A1FFAR4FFAR1TSHRGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |