Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | MRGPRX2 | Q96LB1 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246658 | 0.90 | SLC6A4 (0.68) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL11246645 | 0.90 | SLC6A4 (0.68) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| Bromide SCHEMBL11266393 | 0.89 | SLC6A4 (0.66) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL11185245 | 0.89 | SLC6A4 (0.75) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL11535102 | 0.89 | SLC6A4 (0.75) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| Bromide SCHEMBL11252035 | 0.89 | SLC6A4 (0.66) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL11185241 | 0.89 | SLC6A4 (0.75) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL11185531 | 0.89 | SLC6A4 (0.75) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL3207570 | 0.86 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL10994891 | 0.84 | SLC6A4 (0.79) | SLC6A2SLC6A4SLC6A3CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170333426-A1 | 1,2,4-Triazolo [4,3-A] Pyridine Derivatives And Their Use For The Treatment Of Prevention Of Neurological And Psychiatric Disorders | JANSSEN PHARMACEUTICALS INC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170333426-A1 | 1,2,4-Triazolo [4,3-A] Pyridine Derivatives And Their Use For The Treatment Of Prevention Of Neurological And Psychiatric Disorders | GRM2, GRM1, GRIN2C | SLC6A2 215/4885SLC6A4 198/4885SLC6A3 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.