Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456962 | 0.80 | — | — | |
| SCHEMBL2344033 | 0.76 | HSD17B10 (0.36) | TSHR | |
| SCHEMBL14002031 | 0.74 | — | — | |
| SCHEMBL7997017 | 0.74 | CETP (0.36) | TSHR | |
| SCHEMBL10306106 | 0.74 | CYP4F2 (0.38) | ALDH1A1 | |
| SCHEMBL24806003 | 0.74 | GRIN2D (0.34) | — | |
| SCHEMBL29076312 | 0.74 | TSHR (0.35) | TSHR | |
| SCHEMBL3624651 | 0.74 | — | — | |
| SCHEMBL5182438 | 0.74 | — | — | |
| SCHEMBL9636003 | 0.72 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509957-A1 | CYSTEINE PROTEASE INHIBITORS | Medivir UK Ltd (GB) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070541-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR UK LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |