Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.39 |
| ▸ | SCN1A | P35498 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627609 | 1.00 | CNR1 (0.41) | CNR1SCN8ASCN1ADYRK1ASCN5A | |
| SCHEMBL19627625 | 0.95 | SCN8A (0.37) | CNR1SCN8ASCN1ADYRK1ASCN5A | |
| SCHEMBL19631765 | 0.94 | CNR1 (0.41) | CNR1SCN8ASCN1ADYRK1ASCN5A | |
| SCHEMBL19631557 | 0.94 | CNR1 (0.41) | CNR1SCN8ASCN1ADYRK1ASCN5A | |
| SCHEMBL29447346 | 0.94 | CNR1 (0.41) | CNR1SCN8ASCN1ADYRK1ASCN5A | |
| SCHEMBL29447377 | 0.94 | CNR1 (0.41) | CNR1SCN8ASCN1ADYRK1ASCN5A | |
| SCHEMBL19627616 | 0.90 | SCN8A (0.39) | SCN8ASCN1ADYRK1AALDH1A1PIK3CA | |
| SCHEMBL19627639 | 0.89 | SCN8A (0.40) | SCN8ASCN1APIK3CAPRKDCMTOR | |
| SCHEMBL19627638 | 0.89 | SCN8A (0.40) | SCN8ASCN1APIK3CAPRKDCMTOR | |
| SCHEMBL19614233 | 0.88 | SCN8A (0.37) | CNR1SCN8ASCN1ADYRK1ABMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334902-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334902-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | SCN1A, SCN1B, SCN2B | CNR1 445/4885SCN8A 14/4885SCN1A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.