Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628261 | 1.00 | KDM4E (0.46) | KDM4ETAS1R3TAS1R1HPGDADORA2A | |
| SCHEMBL26998505 | 0.86 | KDM4E (0.40) | KDM4ETAS1R3TAS1R1ADORA2AALDH1A1 | |
| SCHEMBL26998503 | 0.86 | KDM4E (0.40) | KDM4ETAS1R3TAS1R1ADORA2AALDH1A1 | |
| SCHEMBL19604056 | 0.85 | KDM4E (0.44) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL26998507 | 0.82 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1ADORA2AALDH1A1 | |
| SCHEMBL26998509 | 0.82 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1ADORA2AALDH1A1 | |
| SCHEMBL19628248 | 0.82 | ADORA1 (0.42) | ADORA2AMEN1KMT2A | |
| SCHEMBL19628258 | 0.82 | ADORA1 (0.42) | ADORA2AMEN1KMT2A | |
| SCHEMBL26998497 | 0.80 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1ADORA2AALDH1A1 | |
| SCHEMBL26998499 | 0.80 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1ADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198775-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES | ETH ZURICH (CH) | 2017-11-23 | — | — | WO | disclosed |