Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582602 | 0.84 | TSHR (0.46) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL16469354 | 0.79 | TSHR (0.46) | TSHRTP53TDP1PPARDHMGCR | |
| SCHEMBL13657439 | 0.78 | TSHR (0.50) | TSHRTP53TDP1PPARDHMGCR | |
| SCHEMBL9115350 | 0.78 | TSHR (0.50) | TSHRTP53TDP1PPARDHMGCR | |
| SCHEMBL11737002 | 0.77 | TSHR (0.43) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL2962705 | 0.77 | CYP3A4 (0.54) | TSHR | |
| SCHEMBL11778957 | 0.75 | PPARD (0.43) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL3393814 | 0.75 | TSHR (0.42) | TSHRTP53TDP1PPARD | |
| SCHEMBL9115357 | 0.74 | TSHR (0.46) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL11507905 | 0.74 | TSHR (0.46) | TSHRTP53TDP1PPARDHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334937-A1 | PYRIMIDINE PHOSPHONIC ACID ESTERS | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334937-A1 | PYRIMIDINE PHOSPHONIC ACID ESTERS | TYMP, DPYD, PPA1 | TSHR 4156/4885TP53 612/4885TDP1 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.