Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 3/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27710885 | 0.81 | KDM2B (0.51) | KDM2BPHF8KDM5AKDM5BCYP2E1 | |
| SCHEMBL30030674 | 0.81 | CCR1 (0.68) | KDM2BPHF8KDM5AKDM5BCYP2E1 | |
| SCHEMBL827247 | 0.79 | CCR1 (0.48) | CCR1CCR5CCR8ALDH1A1MAPT | |
| SCHEMBL19628763 | 0.78 | KDM5B (0.62) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL24244214 | 0.75 | KDM2B (0.49) | KDM2BPHF8KDM5AKDM5BCYP2E1 | |
| SCHEMBL23119743 | 0.74 | JMJD6 (0.57) | KDM5BCCR1CCR5CCR8KDM4A | |
| SCHEMBL16034025 | 0.74 | KDM2B (0.48) | KDM2BPHF8KDM5AKDM5BCYP2E1 | |
| SCHEMBL12075252 | 0.73 | KDM4E (0.56) | KDM2BPHF8KDM5AKDM5BCYP2E1 | |
| SCHEMBL23539461 | 0.73 | CYP2E1 (0.56) | KDM5BCYP2E1CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL30042352 | 0.73 | CYP2E1 (0.56) | KDM5BCYP2E1CYP2A6CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334879-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170334879-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334879-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM3B | KDM2B 19/4885PHF8 30/4885KDM5A 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.