Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.78 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.78 |
| ▸ | RPTOR | Q8N122 | 7/20 | 0.78 |
| ▸ | MLST8 | Q9BVC4 | 7/20 | 0.78 |
| ▸ | RICTOR | Q6R327 | 6/20 | 0.78 |
| ▸ | MAPKAP1 | Q9BPZ7 | 6/20 | 0.78 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.54 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24398697 | 0.91 | MTOR (0.92) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL29879987 | 0.91 | MTOR (0.92) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL17748652 | 0.91 | MTOR (0.92) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL17748740 | 0.91 | MTOR (0.92) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL21682466 | 0.88 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL17748755 | 0.88 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL17748759 | 0.88 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL17748739 | 0.83 | MTOR (0.87) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL17748742 | 0.83 | MTOR (0.87) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL17748707 | 0.83 | MTOR (0.78) | MTORPIK3CARPTORMLST8RICTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458067-B1 | TREATMENT OF NEUROLOGICAL DISORDERS | PIQUR THERAPEUTICS AG (CH) | 2020-12-30 | — | — | EP | disclosed |
| WO-2017198346-A1 | TREATMENT OF NEUROLOGICAL DISORDERS | PIQUR THERAPEUTICS AG (CH) | 2017-11-23 | — | — | WO | disclosed |