Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 15/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631099 | 0.83 | LCK (0.44) | LCKNPC1RAB9A | |
| SCHEMBL19630784 | 0.82 | LCK (0.51) | LCKMAPTNPC1RAB9A | |
| SCHEMBL19630738 | 0.82 | LCK (0.51) | LCKMAPTNPC1RAB9A | |
| SCHEMBL19630737 | 0.80 | LCK (0.51) | LCK | |
| SCHEMBL19630788 | 0.79 | LCK (0.52) | LCKMAPTNPC1RAB9A | |
| SCHEMBL2919547 | 0.77 | LCK (0.55) | LCKMAPT | |
| SCHEMBL13846520 | 0.77 | LCK (0.58) | LCKMAPT | |
| SCHEMBL23054101 | 0.76 | LCK (0.57) | LCKMAPT | |
| SCHEMBL19630789 | 0.76 | LCK (0.52) | LCKMAPTNPC1RAB9A | |
| SCHEMBL2274858 | 0.75 | LCK (0.61) | LCKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201313-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | JIN SHENGKAN (US) | 2017-11-23 | — | — | WO | disclosed |