Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | XBP1 | P17861 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 3/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631304 | 0.86 | KDR (0.67) | KDM4ESMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL21356567 | 0.86 | KDR (0.67) | KDM4ESMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL19631346 | 0.86 | NPC1 (0.69) | KDM4ESMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL5284425 | 0.83 | TRPV1 (0.71) | KDM4ESMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL5284418 | 0.83 | TRPV1 (0.71) | KDM4ESMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL19616647 | 0.82 | NPC1 (0.76) | KDM4ESMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL19631296 | 0.81 | KDM4E (0.69) | KDM4ESMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL5909673 | 0.81 | KDR (0.65) | KDM4ESMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL5909669 | 0.81 | KDR (0.65) | KDM4ESMN1; SMN2NPC1RAB9AMITF | |
| SCHEMBL29647749 | 0.81 | KDR (0.81) | KDM4ESMN1; SMN2NPC1RAB9AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346563-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | UNIV TAIPEI MEDICAL (TW) | 2025-11-13 | — | — | US | disclosed |
| US-11427544-B2 | Histone deacetylase 6 inhibitors and use thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-08-30 | — | — | US | disclosed |
| US-20220251043-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-08-11 | — | — | US | disclosed |
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021013163-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | TAIPEI MEDICAL UNIVERSITY (CN) | 2021-01-28 | — | — | WO | disclosed |
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2019-09-19 | — | — | US | disclosed |
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2019-09-19 | — | — | US | disclosed |
| WO-2017200966-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | HDAC1, HDAC11, HDAC7 | KDM4E 216/4885SMN1; SMN2 3282/4885KMT2A 77/4885 |
| US-20250346563-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | HDAC1, HDAC3, HDAC5 | KDM4E 480/4885SMN1; SMN2 574/4885KMT2A 78/4885 |
| US-20220251043-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | HDAC1, HDAC3, HDAC2 | KDM4E 424/4885SMN1; SMN2 722/4885KMT2A 60/4885 |
| US-11427544-B2 | Histone deacetylase 6 inhibitors and use thereof | HDAC1, HDAC11, HDAC7 | KDM4E 216/4885SMN1; SMN2 3282/4885KMT2A 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.