SCHEMBL19632006

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15223780	0.85	HRH4 (0.41)	RAB9ASMN1; SMN2MAPTKDM4EPOLB
	SCHEMBL22147857	0.83	PTGS1 (0.54)	RAB9ASMN1; SMN2MAPTKDM4EPOLB
	SCHEMBL29183557	0.82	KDM4E (0.63)	RAB9ASMN1; SMN2MAPTKDM4EPOLB
	SCHEMBL1500262	0.80	PIK3CG (0.51)	RAB9ASMN1; SMN2KDM4EPOLBEGLN1
	SCHEMBL19632076	0.79	HRH4 (0.37)	RAB9ASMN1; SMN2MAPTKDM4EPOLB
	SCHEMBL15222278	0.79	MAP3K5 (0.39)	RAB9ASMN1; SMN2MAPTKDM4EPOLB
	SCHEMBL2087833	0.78	PTGS1 (0.45)	RAB9ASMN1; SMN2MAPTKDM4EPOLB
	SCHEMBL19592549	0.77	POLB (0.48)	RAB9ASMN1; SMN2MAPTKDM4EPOLB
	SCHEMBL24247758	0.77	APP (0.48)	RAB9ASMN1; SMN2MAPTKDM4EPOLB
	SCHEMBL15223848	0.76	MCHR1 (0.49)	POLBEGLN1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.