Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19632058 | 1.00 | HRH1 (0.38) | HRH1HRH2GRM4HRH3OPRM1 | |
| SCHEMBL19632057 | 0.97 | HRH1 (0.39) | HRH1HRH2GRM4OPRM1GAA | |
| SCHEMBL19631691 | 0.90 | GRM4 (0.37) | HRH1HRH2GRM4HRH3OPRM1 | |
| SCHEMBL19631612 | 0.89 | GRM4 (0.37) | GRM4OPRM1HTR1AHTR2ADRD2 | |
| SCHEMBL19631589 | 0.88 | GRM4 (0.36) | HRH1HRH2GRM4HRH3OPRM1 | |
| SCHEMBL19631998 | 0.86 | GRM4 (0.38) | GRM4OPRM1DRD2 | |
| SCHEMBL19631852 | 0.86 | GRM4 (0.38) | GRM4OPRM1DRD2 | |
| SCHEMBL19631839 | 0.86 | GRM4 (0.38) | GRM4OPRM1DRD2 | |
| SCHEMBL19631856 | 0.85 | GRM4 (0.36) | GRM4 | |
| SCHEMBL19631922 | 0.85 | GRM4 (0.36) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198339-A1 | TETRAHYDROPYRAN AND THIOPYRAN DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2017-11-23 | — | — | WO | disclosed |