Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.52 |
| ▸ | KIT | P10721 | 11/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595645 | 0.76 | GRIA1 (0.43) | LRRK2KIT | |
| SCHEMBL2595531 | 0.76 | KIT (0.43) | KITAKT1 | |
| SCHEMBL2589975 | 0.73 | KIT (0.51) | KITAKT1 | |
| SCHEMBL19617717 | 0.72 | MAP3K5 (0.49) | LRRK2AKT1 | |
| SCHEMBL9966954 | 0.72 | AKT1 (0.85) | KITAKT1 | |
| SCHEMBL2596050 | 0.72 | PRKDC (0.45) | LRRK2 | |
| Hydrochloric Acid SCHEMBL21979540 | 0.71 | AKT1 (0.82) | KITAKT1 | |
| Hydrochloric Acid SCHEMBL15456486 | 0.71 | AKT1 (0.82) | KITAKT1 | |
| SCHEMBL29286044 | 0.71 | USP30 (0.51) | LRRK2 | |
| SCHEMBL30989225 | 0.71 | USP30 (0.51) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292189-A1 | LIM KINASE INHIBITORS | VIRONGY, LLC | 2019-09-26 | — | — | US | disclosed |
| WO-2017201187-A1 | LIM KINASE INHIBITORS | VIRONGY, LLC (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292189-A1 | LIM KINASE INHIBITORS | LIMK1, LIMK2, LIMA1 | LRRK2 141/4885KIT 3580/4885AKT1 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.