⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994219 | 1.00 | — | — | |
| SCHEMBL4343125 | 1.00 | — | — | |
| SCHEMBL10897289 | 0.71 | — | — | |
| Water SCHEMBL11043959 | 0.71 | TSHR (0.44) | — | |
| SCHEMBL109553 | 0.71 | — | — | |
| SCHEMBL2265867 | 0.69 | — | — | |
| SCHEMBL3127247 | 0.69 | — | — | |
| SCHEMBL2265864 | 0.69 | — | — | |
| SCHEMBL13278714 | 0.69 | — | — | |
| SCHEMBL13278716 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092791-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-21 | — | — | US | claimed |
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-01-11 | — | — | US | claimed |
| CN-111936496-B | Heterocyclic compounds useful as medicaments | 马萨里克大学 | 2023-12-29 | — | — | CN | claimed |
| EP-4263549-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-10-25 | — | — | EP | claimed |
| US-20230072933-A1 | PPARG Modulators for the Treatment of Osteoporosis | SCRIPPS RESEARCH INST (US) | 2023-03-09 | — | — | US | claimed |
| US-11498920-B2 | 4-(1H-imidazol-5-yl)-1H-pyrrolo[2, 3-b] pyridines for use in the treatment of leukaemias, lymphomas and solid tumors | MASARYKOVA UNIVERZITA (CZ) | 2022-11-15 | — | — | US | claimed |
| WO-2022128848-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-06-23 | — | — | WO | claimed |
| US-11326164-B2 | Trimethylglycylglycerin compositions and their use in developing anti-cancer drugs and RNA vaccines | WJWU & LYNN INSTITUTE FOR STEM CELL RES (US) | 2022-05-10 | — | — | US | claimed |
| EP-3774795-B1 | 4-(1H- IMIDAZOL- 5- YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS | UNIV MASARYKOVA (CZ) | 2022-03-16 | — | — | EP | claimed |
| WO-2021061192-A1 | NOVEL TRIMETHYLGLYCYLGLYCERIN COMPOSITIONS AND THEIR USE IN DEVELOPING ANTI-CANCER DRUGS AND RNA VACCINES | WJWU & LYNN INSTITUTE FOR STEM CELL RESEARCH (US) | 2021-04-01 | — | — | WO | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| US-5789439-A | SKIN ULCERS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1998-08-04 | — | — | US | claimed |
| EP-0448029-B1 | Novel pharmaceutical uses of forskolin derivatives | NIPPON KAYAKU KK (JP) | 1995-12-20 | — | — | EP | claimed |
| EP-0650723-A2 | Novel pharmaceutical use of forskolin derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1995-05-03 | — | — | EP | claimed |
| US-5302730-A | Acylation with acetic acid at positions one and seven; eliminating acyl group at position seven by solvolysis | NIPPON KAYAKU KK (JP) | 1994-04-12 | — | — | US | claimed |
| EP-0448029-A2 | Novel pharmaceutical uses of forskolin derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-09-25 | — | — | EP | claimed |
| US-4892867-A | Antiandrogenic 17-alpha-alkyl steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-01-09 | — | — | US | claimed |
| US-4344941-A | Antiandrogenic 17α-substituted steroids | SCHERING AKTIENGESELLSCHAFT (A.G.) (DE) | 1982-08-17 | — | — | US | claimed |