Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633114 | 0.85 | GRM2 (1.00) | GRM2KCNH2 | |
| SCHEMBL19633121 | 0.81 | GRM2 (0.54) | GRM2KCNH2MAPK1 | |
| SCHEMBL19633030 | 0.74 | GRM2 (1.00) | GRM2KCNH2MAPK1 | |
| SCHEMBL24017785 | 0.73 | GRM2 (1.00) | GRM2KCNH2 | |
| SCHEMBL19633187 | 0.73 | GRM2 (1.00) | GRM2KCNH2 | |
| SCHEMBL19633126 | 0.69 | GRM2 (0.77) | GRM2KCNH2 | |
| SCHEMBL19633120 | 0.69 | GRM2 (1.00) | GRM2KCNH2 | |
| SCHEMBL19633122 | 0.68 | GRM2 (1.00) | GRM2KCNH2 | |
| SCHEMBL19633007 | 0.68 | GRM2 (0.83) | GRM2KCNH2MAPK1 | |
| SCHEMBL19633161 | 0.68 | GRM2 (0.74) | GRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198180-A1 | FLUORINE-CONTAINING TRIAZOLOPYRIDINE, AND MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | 中国科学院上海药物研究所 | 2017-11-23 | — | — | WO | disclosed |