Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 5/20 | 0.60 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.56 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.56 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073376 | 0.90 | GAK (0.69) | GAKPKMYT1RIPK2COQ8ANLK | |
| SCHEMBL19633658 | 0.90 | PKMYT1 (0.63) | GAKPKMYT1RIPK2COQ8ANLK | |
| SCHEMBL19633676 | 0.90 | GAK (0.68) | GAKRIPK2COQ8ANLKEGFR | |
| SCHEMBL30420470 | 0.88 | GAK (0.67) | GAKRIPK2COQ8ANLKRET | |
| SCHEMBL23706787 | 0.86 | GAK (0.61) | GAKRIPK2COQ8ANLKRET | |
| SCHEMBL19633647 | 0.86 | GAK (0.66) | GAKRIPK2COQ8ANLKEGFR | |
| SCHEMBL30420414 | 0.85 | HTT (0.64) | GAKRIPK2COQ8ANLKKDR | |
| SCHEMBL21121509 | 0.85 | HTT (0.64) | GAKRIPK2COQ8ANLKKDR | |
| SCHEMBL21121679 | 0.85 | HTT (0.64) | GAKRIPK2COQ8ANLKKDR | |
| SCHEMBL30419610 | 0.85 | HTT (0.64) | GAKRIPK2COQ8ANLKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852001-B | Bridged biquinoline compound and preparation method and application thereof | 中山大学 | 2025-05-20 | — | — | CN | disclosed |
| CN-118852001-A | Bridged biquinoline compound and preparation method and application thereof | 中山大学 | 2024-10-29 | — | — | CN | disclosed |
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |