Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 13/20 | 0.67 |
| ▸ | SCN1A | P35498 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633998 | 0.95 | SCN8A (0.68) | SCN8ASCN1A | |
| SCHEMBL19634142 | 0.84 | SCN8A (0.67) | SCN8ASCN1A | |
| SCHEMBL19613070 | 0.80 | SCN8A (1.00) | SCN8ASCN1A | |
| SCHEMBL19634062 | 0.78 | SCN8A (0.70) | SCN8ASCN1A | |
| SCHEMBL19634196 | 0.78 | SCN8A (0.69) | SCN8ASCN1A | |
| SCHEMBL19634138 | 0.76 | SCN8A (0.61) | SCN8ASCN1A | |
| SCHEMBL19634122 | 0.76 | SCN8A (0.66) | SCN8ASCN1A | |
| SCHEMBL19613907 | 0.75 | SCN8A (1.00) | SCN8ASCN1A | |
| SCHEMBL19613152 | 0.75 | SCN8A (1.00) | SCN8ASCN1A | |
| SCHEMBL19613153 | 0.75 | SCN8A (1.00) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |