Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 19/20 | 0.50 |
| ▸ | SCN1A | P35498 | 13/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634127 | 0.85 | SCN8A (0.48) | SCN8ASCN1AMEN1ALDH1A1KMT2A | |
| SCHEMBL19613751 | 0.84 | SCN8A (0.59) | SCN8ASCN1A | |
| SCHEMBL19613752 | 0.84 | SCN8A (0.59) | SCN8ASCN1A | |
| SCHEMBL19634129 | 0.84 | SCN8A (0.47) | SCN8ASCN1AKDM4EMEN1ALDH1A1 | |
| SCHEMBL19614031 | 0.75 | SCN8A (0.63) | SCN8ASCN1A | |
| SCHEMBL19614029 | 0.75 | SCN8A (0.63) | SCN8ASCN1A | |
| SCHEMBL19613703 | 0.75 | SCN8A (0.54) | SCN8ASCN1A | |
| SCHEMBL19613705 | 0.75 | SCN8A (0.54) | SCN8ASCN1A | |
| SCHEMBL19634196 | 0.74 | SCN8A (0.69) | SCN8ASCN1A | |
| SCHEMBL22088316 | 0.72 | CYP1A2 (0.36) | KDM4EMEN1ALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |