Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 19/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631463 | 0.89 | DHODH (0.57) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631444 | 0.87 | DHODH (0.77) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631459 | 0.85 | DHODH (0.84) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631622 | 0.81 | DHODH (0.56) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631394 | 0.80 | DHODH (0.79) | DHODH | |
| SCHEMBL19631395 | 0.79 | DHODH (0.82) | DHODH | |
| SCHEMBL19631383 | 0.77 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL30131137 | 0.77 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL19631366 | 0.76 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT | |
| SCHEMBL30131181 | 0.76 | DHODH (1.00) | DHODHKDM4EALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198178-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | 华东理工大学 | 2017-11-23 | — | — | WO | disclosed |