Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 16/20 | 0.42 |
| ▸ | SCN1A | P35498 | 14/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634021 | 0.85 | SCN8A (0.44) | SCN8ASCN1A | |
| SCHEMBL19634135 | 0.85 | SCN8A (0.41) | SCN8ASCN1ASCN9A | |
| SCHEMBL19633938 | 0.81 | SCN8A (0.42) | SCN8ASCN1A | |
| SCHEMBL19631505 | 0.80 | SCN8A (0.64) | SCN8ASCN1A | |
| SCHEMBL19634098 | 0.80 | SCN8A (0.64) | SCN8ASCN1A | |
| SCHEMBL19627598 | 0.80 | SCN8A (0.64) | SCN8ASCN1A | |
| SCHEMBL19634019 | 0.78 | SCN8A (0.70) | SCN8ASCN1A | |
| SCHEMBL19634224 | 0.75 | SCN8A (0.72) | SCN8ASCN1A | |
| SCHEMBL19633996 | 0.75 | SCN8A (0.72) | SCN8ASCN1A | |
| Trifluoroacetic Acid SCHEMBL19613778 | 0.74 | SCN8A (0.59) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |