Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 15/20 | 0.67 |
| ▸ | SCN8A | Q9UQD0 | 15/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634128 | 0.86 | SCN8A (0.68) | SCN1ASCN8ASMN1; SMN2KCNH2SCN5A | |
| SCHEMBL19633913 | 0.82 | SCN8A (0.49) | SCN1ASCN8ASMN1; SMN2GAASCN9A | |
| SCHEMBL19634055 | 0.82 | SCN8A (0.60) | SCN1ASCN8A | |
| SCHEMBL19613526 | 0.80 | SCN8A (1.00) | SCN1ASCN8A | |
| SCHEMBL19633983 | 0.78 | SCN8A (0.67) | SCN1ASCN8A | |
| SCHEMBL19634142 | 0.78 | SCN8A (0.67) | SCN1ASCN8A | |
| SCHEMBL19633943 | 0.76 | SCN8A (0.71) | SCN1ASCN8A | |
| SCHEMBL19613660 | 0.76 | SCN8A (1.00) | SCN1ASCN8ASCN5A | |
| Trifluoroacetic Acid SCHEMBL19613870 | 0.76 | SCN8A (0.89) | SCN1ASCN8A | |
| SCHEMBL19634218 | 0.75 | SCN8A (0.54) | SCN1ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |