SCHEMBL19634113

SCHEMBL19634113

CC1C[C@@H](Oc2ccc(S(=O)(=O)Nc3nccs3)cc2Cl)CCN1Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 1.00
SCN1A P35498 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19612867 1.00 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19614128 1.00 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19612866 1.00 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19614131 1.00 SCN8A (1.00) SCN8ASCN1A
SCHEMBL22590182 0.91 SCN8A (0.83) SCN8ASCN1A
SCHEMBL22590186 0.91 SCN8A (0.83) SCN8ASCN1A
SCHEMBL19631657 0.91 SCN8A (0.83) SCN8ASCN1A
SCHEMBL19613332 0.87 SCN8A (1.00) SCN8ASCN1A
SCHEMBL21117619 0.84 SCN8A (0.75) SCN8ASCN1A
SCHEMBL19613409 0.84 SCN8A (1.00) SCN8ASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017201468-A1 BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2017-11-23 WO disclosed