Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 17/20 | 0.57 |
| ▸ | PMAIP1 | Q13794 | 11/20 | 0.57 |
| ▸ | BAD | Q92934 | 6/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | BCL2 | P10415 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23251228 | 0.95 | MCL1 (0.58) | MCL1PMAIP1BADBCL2L1ALB | |
| SCHEMBL19635009 | 0.93 | MCL1 (0.57) | MCL1PMAIP1BADBCL2L1ALB | |
| SCHEMBL19615243 | 0.91 | MCL1 (0.68) | MCL1PMAIP1BADBCL2L1ALB | |
| SCHEMBL23251298 | 0.90 | MCL1 (0.68) | MCL1PMAIP1BADBCL2L1ALB | |
| SCHEMBL19635132 | 0.90 | BAD (0.56) | MCL1PMAIP1BADBCL2L1BCL2 | |
| SCHEMBL19615073 | 0.89 | MCL1 (0.67) | MCL1PMAIP1BADBCL2L1ALB | |
| SCHEMBL19635899 | 0.87 | MCL1 (0.56) | MCL1PMAIP1BADBCL2L1BCL2 | |
| SCHEMBL19635833 | 0.87 | MCL1 (0.55) | MCL1PMAIP1BADBCL2L1ALB | |
| SCHEMBL19634964 | 0.87 | MCL1 (0.55) | MCL1PMAIP1BADBCL2L1BCL2 | |
| SCHEMBL19635335 | 0.86 | MCL1 (0.55) | MCL1PMAIP1BADBCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |