Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 20/20 | 0.59 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | PMAIP1 | Q13794 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24378004 | 0.96 | MCL1 (0.56) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL19635314 | 0.90 | MCL1 (0.52) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL23251257 | 0.90 | MCL1 (0.65) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL19635308 | 0.90 | MCL1 (0.56) | MCL1BCL2ALBPMAIP1 | |
| Hydrochloric Acid SCHEMBL29602080 | 0.90 | MCL1 (0.65) | MCL1BCL2ALBPMAIP1 | |
| Hydrochloric Acid SCHEMBL19616004 | 0.90 | MCL1 (0.65) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL24378192 | 0.90 | MCL1 (0.54) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL19635442 | 0.86 | MCL1 (0.67) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL19635248 | 0.86 | MCL1 (0.62) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL19635261 | 0.86 | MCL1 (0.59) | MCL1BCL2ALBPMAIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |