Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 8/20 | 0.54 |
| ▸ | BAD | Q92934 | 8/20 | 0.54 |
| ▸ | BCL2 | P10415 | 7/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635627 | 0.90 | MCL1 (0.61) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL19635763 | 0.90 | BAD (0.56) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL19635149 | 0.86 | MCL1 (0.53) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL24378186 | 0.86 | MCL1 (0.61) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL24378084 | 0.84 | BCL2 (0.59) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL19615065 | 0.81 | BAD (0.76) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL19635729 | 0.81 | BAD (0.61) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL19635539 | 0.80 | BCL2L1 (0.54) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL19635033 | 0.79 | MCL1 (0.55) | BCL2L1BADBCL2MCL1 | |
| SCHEMBL19615572 | 0.78 | MCL1 (0.58) | BCL2L1BADBCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |