Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 17/20 | 0.54 |
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | PMAIP1 | Q13794 | 5/20 | 0.42 |
| ▸ | BCL2 | P10415 | 4/20 | 0.42 |
| ▸ | BAD | Q92934 | 4/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635407 | 0.92 | MCL1 (0.58) | MCL1ALBPMAIP1BCL2BAD | |
| SCHEMBL24378037 | 0.90 | MCL1 (0.59) | MCL1ALBPMAIP1BCL2BAD | |
| SCHEMBL24378076 | 0.89 | MCL1 (0.58) | MCL1ALBPMAIP1BCL2BAD | |
| SCHEMBL19635401 | 0.87 | MCL1 (0.56) | MCL1ALBPMAIP1BCL2BAD | |
| Hydrochloric Acid SCHEMBL19615332 | 0.86 | MCL1 (0.55) | MCL1ALBPMAIP1BCL2BAD | |
| Hydrochloric Acid SCHEMBL29602490 | 0.86 | MCL1 (0.55) | MCL1ALBPMAIP1BCL2BAD | |
| SCHEMBL19635871 | 0.85 | MCL1 (0.52) | MCL1ALBPMAIP1BCL2BAD | |
| SCHEMBL19634936 | 0.82 | MCL1 (0.59) | MCL1ALBPMAIP1BCL2BAD | |
| Hydrochloric Acid SCHEMBL19615256 | 0.82 | MCL1 (0.58) | MCL1ALBPMAIP1BCL2BAD | |
| Hydrochloric Acid SCHEMBL29602336 | 0.82 | MCL1 (0.58) | MCL1ALBPMAIP1BCL2BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |