Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.91 |
| ▸ | EGFR | P00533 | 2/20 | 0.91 |
| ▸ | SRC | P12931 | 1/20 | 0.91 |
| ▸ | BMX | P51813 | 1/20 | 0.91 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15669535 | 0.95 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15691525 | 0.95 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15669886 | 0.95 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL19636166 | 0.95 | BTK (0.82) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15669529 | 0.89 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15669832 | 0.87 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15691529 | 0.87 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15691646 | 0.87 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15670231 | 0.87 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15691594 | 0.87 | BTK (1.00) | BTKEGFRSRCBMXNR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459940-B1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | SUZHOU SINOVENT PHARMACEUTICALS CO LTD (CN) | 2022-07-20 | — | — | EP | disclosed |
| US-10882843-B2 | 5-aminopyrazole carboxamide derivative as BTK inhibitor and preparation method and pharmaceutical composition thereof | Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) | 2021-01-05 | — | — | US | disclosed |
| US-10882843-B2 | 5-aminopyrazole carboxamide derivative as BTK inhibitor and preparation method and pharmaceutical composition thereof | Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) | 2021-01-05 | — | — | US | disclosed |
| CN-107382973-B | 5-aminopyrazole carboxamide derivatives as BTK inhibitors, process for their preparation and pharmaceutical compositions containing them | 苏州信诺维医药科技有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-20190152952-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2019-05-23 | — | — | US | disclosed |
| US-20190152952-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2019-05-23 | — | — | US | disclosed |
| EP-3459940-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | Zhejiang Yukon Pharma Co., Ltd. (CN) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017198050-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | 浙江予川医药科技有限公司 | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10882843-B2 | 5-aminopyrazole carboxamide derivative as BTK inhibitor and preparation method and pharmaceutical composition thereof | BTK, SYK, LCK | BTK 1/4885EGFR 607/4885SRC 22/4885 |
| US-20190152952-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | BTK, SYK, LCK | BTK 1/4885EGFR 607/4885SRC 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.