Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAD | Q92934 | 8/20 | 0.60 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 14/20 | 0.54 |
| ▸ | BCL2 | P10415 | 4/20 | 0.54 |
| ▸ | PMAIP1 | Q13794 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19615063 | 0.93 | BAD (0.67) | BADBCL2L1MCL1BCL2PMAIP1 | |
| SCHEMBL19635210 | 0.91 | BAD (0.59) | BADBCL2L1MCL1BCL2PMAIP1 | |
| SCHEMBL21802187 | 0.88 | BAD (0.74) | BADBCL2L1MCL1BCL2PMAIP1 | |
| SCHEMBL19616014 | 0.81 | MCL1 (0.80) | BADBCL2L1MCL1BCL2 | |
| SCHEMBL19635504 | 0.80 | MCL1 (0.70) | BADBCL2L1MCL1BCL2 | |
| SCHEMBL19635211 | 0.79 | MCL1 (0.51) | BADBCL2L1MCL1BCL2PMAIP1 | |
| SCHEMBL19615161 | 0.78 | MCL1 (0.72) | BADBCL2L1MCL1BCL2PMAIP1 | |
| SCHEMBL19635885 | 0.78 | MCL1 (0.64) | BADBCL2L1MCL1BCL2PMAIP1 | |
| SCHEMBL19635411 | 0.78 | MCL1 (0.85) | BADBCL2L1MCL1BCL2PMAIP1 | |
| SCHEMBL19615371 | 0.78 | MCL1 (0.66) | BADBCL2L1MCL1BCL2PMAIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |