Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.74 |
| ▸ | EGFR | P00533 | 8/20 | 0.74 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19636122 | 1.00 | BTK (0.74) | BTKEGFRSRC | |
| SCHEMBL19636125 | 1.00 | BTK (0.74) | BTKEGFRSRC | |
| SCHEMBL19636128 | 1.00 | BTK (0.74) | BTKEGFRSRC | |
| SCHEMBL19635981 | 1.00 | BTK (0.74) | BTKEGFRSRC | |
| SCHEMBL19636121 | 1.00 | BTK (0.74) | BTKEGFRSRC | |
| SCHEMBL19636123 | 1.00 | BTK (0.74) | BTKEGFRSRC | |
| SCHEMBL19636105 | 0.86 | BTK (0.91) | BTKEGFRSRC | |
| SCHEMBL19636095 | 0.86 | BTK (0.85) | BTKEGFRSRC | |
| SCHEMBL19635988 | 0.85 | BTK (0.76) | BTKEGFRSRC | |
| SCHEMBL15670276 | 0.85 | BTK (1.00) | BTKEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198050-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | 浙江予川医药科技有限公司 | 2017-11-23 | — | — | WO | disclosed |