Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19637202 | 0.93 | KRAS (0.62) | KRASSOS1 | |
| SCHEMBL19637069 | 0.91 | KRAS (0.74) | KRASSOS1 | |
| SCHEMBL21912118 | 0.84 | KRAS (0.63) | KRAS | |
| SCHEMBL25021352 | 0.82 | KRAS (0.63) | KRAS | |
| SCHEMBL19616813 | 0.81 | KRAS (0.60) | KRAS | |
| SCHEMBL19948175 | 0.81 | KRAS (0.60) | KRAS | |
| SCHEMBL19617059 | 0.79 | KRAS (0.60) | KRAS | |
| SCHEMBL22440393 | 0.79 | KRAS (0.60) | KRAS | |
| SCHEMBL19959171 | 0.79 | KRAS (0.65) | KRAS | |
| SCHEMBL20974988 | 0.78 | KRAS (0.56) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201161-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-11-23 | — | — | WO | disclosed |