Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962764 | 0.83 | TSHR (0.46) | USP2CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL1964661 | 0.83 | TSHR (0.46) | USP2CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL1962735 | 0.83 | TSHR (0.46) | USP2CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL1962439 | 0.83 | TSHR (0.46) | USP2CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL1965454 | 0.83 | TSHR (0.46) | USP2CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL8746900 | 0.80 | PLA2G2C (0.53) | USP2CYP3A4MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2232552 | 0.80 | PLA2G2C (0.53) | USP2CYP3A4MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18006545 | 0.77 | TDP1 (0.50) | USP2CYP3A4MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4434202 | 0.75 | TSHR (0.46) | USP2CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL30010586 | 0.74 | TSHR (0.67) | USP2CYP3A4MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |