Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.64 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21725403 | 0.96 | CYP11B1 (0.66) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL19638272 | 0.96 | CYP11B1 (0.66) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL24252784 | 0.93 | CYP11B1 (0.62) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL21725387 | 0.93 | CYP11B1 (0.62) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL23095069 | 0.93 | CYP11B1 (0.62) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL23095068 | 0.92 | CYP11B1 (0.58) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL19762057 | 0.92 | CYP11B1 (0.65) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL14725222 | 0.92 | CYP11B1 (0.68) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL23095070 | 0.91 | CYP11B1 (0.59) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 | |
| SCHEMBL21317598 | 0.91 | CYP11B1 (0.59) | CYP11B1DHODHCYP11B2CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248966-B1 | PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO LTD (JP) | 2022-12-21 | — | — | EP | disclosed |
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20180006239-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO., LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| US-20180006239-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO., LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| EP-3248966-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |
| EP-3248966-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180006239-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES | TYMS, TYMP, DPYD | CYP11B1 2481/4885DHODH 20/4885CYP11B2 2674/4885 |
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | TYMS, TYMP, DPYD | CYP11B1 2481/4885DHODH 20/4885CYP11B2 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.