Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.82 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069348 | 0.90 | BRD4 (1.00) | BRD4HDAC6HDAC1 | |
| SCHEMBL27990765 | 0.84 | BRD4 (0.68) | BRD4HDAC6HDAC1 | |
| SCHEMBL28514566 | 0.82 | BRD4 (0.60) | BRD4HDAC6HDAC1 | |
| SCHEMBL28514563 | 0.81 | BRD4 (0.59) | BRD4HDAC6HDAC1 | |
| SCHEMBL17879721 | 0.80 | BRD4 (0.54) | BRD4 | |
| SCHEMBL15069429 | 0.79 | BRD4 (0.64) | BRD4HDAC6HDAC1 | |
| SCHEMBL19638633 | 0.76 | BRD4 (0.82) | BRD4HDAC6HDAC1 | |
| SCHEMBL28496030 | 0.76 | BRD4 (0.70) | BRD4HDAC6HDAC1 | |
| SCHEMBL30306234 | 0.76 | BRD4 (0.70) | BRD4HDAC6HDAC1 | |
| SCHEMBL28496028 | 0.75 | BRD4 (0.69) | BRD4HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797918-B1 | BROMODOMAIN INHIBITORS | ABBVIE INC (US) | 2017-11-29 | — | — | EP | claimed |