⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamide SCHEMBL5880 | 0.87 | — | — | |
| Sulfamide SCHEMBL3293102 | 0.80 | — | — | |
| Sulfamide SCHEMBL3409127 | 0.80 | — | — | |
| Sulfamide SCHEMBL3827754 | 0.80 | — | — | |
| Sulfamide SCHEMBL17495597 | 0.80 | — | — | |
| Sulfamide SCHEMBL5667325 | 0.80 | — | — | |
| Sulfamide SCHEMBL10866317 | 0.80 | — | — | |
| Sulfamide SCHEMBL1000467 | 0.80 | — | — | |
| Sulfamide SCHEMBL10866319 | 0.80 | — | — | |
| Sulfamide SCHEMBL5067852 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640508-B2 | Diazene directed modular synthesis of compounds with quaternary carbon centers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190119286-A1 | DIAZENE DIRECTED MODULAR SYNTHESIS OF COMPOUNDS WITH QUATERNARY CARBON CENTERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-04-25 | — | — | US | disclosed |
| US-20170342077-A1 | DIAZENE DIRECTED MODULAR SYNTHESIS OF COMPOUNDS WITH QUATERNARY CARBON CENTERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-11-30 | — | — | US | disclosed |
| WO-2017205539-A1 | DIAZENE DIRECTED MODULAR SYNTHESIS OF COMPOUNDS WITH QUATERNARY CARBON CENTERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-11-30 | — | — | WO | disclosed |