Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 1.00 |
| ▸ | TLR7 | Q9NYK1 | 17/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19651888 | 1.00 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL19651954 | 0.95 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL19641830 | 0.93 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL19651939 | 0.91 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL19651890 | 0.90 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL24699640 | 0.88 | TLR8 (0.79) | TLR8TLR7 | |
| SCHEMBL30822808 | 0.88 | TLR8 (0.79) | TLR8TLR7 | |
| SCHEMBL19641892 | 0.88 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL19651977 | 0.88 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL30822795 | 0.87 | TLR8 (0.76) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464245-A1 | BENZAZEPINE DICARBOXAMIDE COMPOUNDS WITH TERTIARY AMIDE FUNCTION | H. Hoffnabb-La Roche Ag (CH) | 2019-04-10 | — | — | EP | claimed |
| WO-2017202704-A1 | BENZAZEPINE DICARBOXAMIDE COMPOUNDS WITH TERTIARY AMIDE FUNCTION | F. HOFFMANN-LA ROCHE AG (CH) | 2017-11-30 | — | — | WO | claimed |
| EP-3464245-A1 | BENZAZEPINE DICARBOXAMIDE COMPOUNDS WITH TERTIARY AMIDE FUNCTION | H. Hoffnabb-La Roche Ag (CH) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017202704-A1 | BENZAZEPINE DICARBOXAMIDE COMPOUNDS WITH TERTIARY AMIDE FUNCTION | F. HOFFMANN-LA ROCHE AG (CH) | 2017-11-30 | — | — | WO | disclosed |