Phosphine

Phosphine

SCHEMBL19641972

CC[N+](c1ccccc1)(c1ccccc1)c1ccccc1.P

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43
TP53 P04637 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PSIP1 O75475 1/20 0.39
ACHE P22303 3/20 0.35
CHRNA7 P36544 3/20 0.35
CHRNB2 P17787 2/20 0.35
CHRNB4 P30926 2/20 0.35
CHRNA3 P32297 2/20 0.35
CHRNA4 P43681 2/20 0.35
TSHR P16473 1/20 0.35
OPRM1 P35372 1/20 0.35
BLM P54132 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125687 0.97 APOBEC3A (0.46) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL636643 0.94 KDM4E (0.44) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
Fluoride Ion SCHEMBL1502858 0.94 APOBEC3A (0.43) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
Bromide SCHEMBL637557 0.94 APOBEC3A (0.43) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
Water SCHEMBL2149535 0.94 APOBEC3A (0.43) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
Iodide SCHEMBL1502919 0.94 APOBEC3A (0.50) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
SCHEMBL2150420 0.87 APOBEC3A (0.39) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
SCHEMBL27754560 0.87 APOBEC3A (0.39) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
SCHEMBL27836884 0.85 APOBEC3A (0.37) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E
Perchlorate SCHEMBL2150227 0.84 APOBEC3A (0.36) APOBEC3AAPOBEC3GTP53ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464416-B1 POLYMERS, PROCESSES, COMPOSITIONS&USES COVESTRO NETHERLANDS BV (NL) 2022-06-22 EP disclosed
EP-3464417-B1 POLYMERS, PROCESSES, COMPOSITIONS & USES COVESTRO NETHERLANDS BV (NL) 2022-06-15 EP disclosed
US-20210179858-A1 POLYMERS, PROCESSES, COMPOSITIONS & USES DSM IP ASSETS B.V. (NL) 2021-06-17 US disclosed
US-20210071012-A1 POLYMERS, PROCESSES, COMPOSITIONS & USES COVESTRO (NETHERLANDS) B.V. (NL) 2021-03-11 US disclosed
US-20210002419-A1 POLYMERS, PROCESSES, COMPOSITIONS & USES DSM IP ASSETS BV (NL) 2021-01-07 US disclosed
US-10875959-B2 Polymers, processes, compositions and uses DSM IP ASSETS B.V. (NL) 2020-12-29 US disclosed
EP-3464418-B1 POLYMERS, PROCESSES, COMPOSITIONS & USES DSM IP ASSETS BV (NL) 2020-11-18 EP disclosed
US-20190292313-A1 POLYMERS, PROCESSES, COMPOSITIONS & USES COVESTRO (NETHERLANDS) B.V. (NL) 2019-09-26 US disclosed
US-20190276677-A1 POLYMERS, PROCESSES, COMPOSITIONS & USES COVESTRO (NETHERLANDS) B.V. (NL) 2019-09-12 US disclosed
CN-109790282-A Polymer, method, composition and purposes 帝斯曼知识产权资产管理有限公司 2019-05-21 CN disclosed
EP-3464416-A1 POLYMERS, PROCESSES, COMPOSITIONS&USES DSM IP Assets B.V. (NL) 2019-04-10 EP disclosed
EP-3464418-A2 POLYMERS, PROCESSES, COMPOSITIONS&USES DSM IP Assets B.V. (NL) 2019-04-10 EP disclosed
EP-3464417-A1 POLYMERS, PROCESSES, COMPOSITIONS&USES DSM IP Assets B.V. (NL) 2019-04-10 EP disclosed
CN-109312060-A Polymers, methods, compositions and uses 帝斯曼知识产权资产管理有限公司 2019-02-05 CN disclosed
CN-109153774-A Polymers, methods, compositions and uses 帝斯曼知识产权资产管理有限公司 2019-01-04 CN disclosed
WO-2017203045-A1 POLYMERS, PROCESSES, COMPOSITIONS & USES DSM IP ASSETS B.V. (NL) 2017-11-30 WO disclosed
WO-2017203044-A2 POLYMERS, PROCESSES, COMPOSITIONS & USES DSM IP ASSETS B.V. (NL) 2017-11-30 WO disclosed
WO-2017203047-A1 POLYMERS, PROCESSES, COMPOSITIONS & USES DSM IP ASSETS B.V. (NL) 2017-11-30 WO disclosed