SCHEMBL1964440

SCHEMBL1964440

Nc1c(F)c(I)c(F)c(I)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18373639 0.87
SCHEMBL31084745 0.86
SCHEMBL6516734 0.80
SCHEMBL18653066 0.78
SCHEMBL19353721 0.78
SCHEMBL6515368 0.72
SCHEMBL9250358 0.72
SCHEMBL9775429 0.72
SCHEMBL18930202 0.72
SCHEMBL20643764 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130034495-A1 ISOTOPOLOGUES OF 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2,4,6-TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-YLAMINO]-CYCLOHEXAN-1-OL SIGNAL PHARMACEUTICALS, LLC 2013-02-07 US disclosed
US-20130034495-A1 ISOTOPOLOGUES OF 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2,4,6-TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-YLAMINO]-CYCLOHEXAN-1-OL SIGNAL PHARMACEUTICALS, LLC 2013-02-07 US disclosed
US-20130034495-A1 ISOTOPOLOGUES OF 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2,4,6-TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-YLAMINO]-CYCLOHEXAN-1-OL SIGNAL PHARMACEUTICALS, LLC 2013-02-07 US disclosed
WO-2011071491-A1 ISOTOPOLOGUES OF 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2, 4, 6- TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-YLAMINO]-CYCLOHEXAN-1-OL SIGNAL PHARMACEUTICALS, LLC (US) 2011-06-16 WO disclosed
WO-2011071491-A1 ISOTOPOLOGUES OF 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2, 4, 6- TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-YLAMINO]-CYCLOHEXAN-1-OL SIGNAL PHARMACEUTICALS, LLC (US) 2011-06-16 WO disclosed