Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18067181 | 1.00 | BTN3A1 (0.54) | BTN3A1LMNATDP1HSD17B10MMP8 | |
| SCHEMBL16566342 | 0.86 | BTN3A1 (0.54) | BTN3A1LMNATDP1MMP8ELANE | |
| SCHEMBL19765980 | 0.85 | BTN3A1 (0.53) | BTN3A1LMNATDP1MMP8ELANE | |
| SCHEMBL18061741 | 0.85 | BTN3A1 (0.53) | BTN3A1LMNATDP1MMP8ELANE | |
| SCHEMBL18067091 | 0.84 | BTN3A1 (0.52) | BTN3A1HSD17B10ELANE | |
| SCHEMBL18067089 | 0.84 | BTN3A1 (0.52) | BTN3A1HSD17B10ELANE | |
| SCHEMBL12746449 | 0.84 | BTN3A1 (0.58) | BTN3A1LMNATDP1ELANEHPGD | |
| SCHEMBL18067134 | 0.84 | BTN3A1 (0.58) | BTN3A1LMNATDP1ELANEHPGD | |
| SCHEMBL18583602 | 0.84 | BTN3A1 (0.58) | BTN3A1LMNATDP1ELANEHPGD | |
| SCHEMBL13921731 | 0.84 | BTN3A1 (0.58) | BTN3A1LMNATDP1ELANEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828410-B2 | β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment | Atea Pharmaceuticals, Inc. (US) | 2017-11-28 | — | — | US | disclosed |